UNC1999 cas: 1431612-23-5

UNC1999 is a potent,orally bioavailable and selective inhibitor of EZH2 and EZH1 with IC50 of 2 nM and 45 nM in cell-free assays,respectively,showing >1000-fold selectivity over a broad range of epigenetic and non-epigenetic targets.UNC1999 is a potent autophagy inducer. UNC1999 specifically suppresses H3K27me3/2 and induces a range of anti-leukemia effects including anti-proliferation,differentiation,and apoptosis.

msds---UNC1999